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Rabbit Anti-RSMB/SNRPB Polyclonal Antibody
Rabbit Anti-RSMB/SNRPB Polyclonal Antibody

Rabbit Anti-RSMB/SNRPB Polyclonal Antibody

产品编号

PAV3483

别名

small nuclear ribonucleoprotein polypeptides B and B1, CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliassmall nuclear ribonucleoprotein polypeptides B and B1, CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B
Catalog NumberPAV3483
Product DescriptionRabbit polyclonal antibody raised against human SNRPB (Small nuclear ribonucleoprotein-associated proteins B and B'). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameSNRPB
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录与RNA加工
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]
ImmunogenThis antibody was raised against from part region of human SNRPB protein (UniProt: P14678)
ApplicationWB
Recommended DilutionWB 1:500-2000
Gene ID6628
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈24.6 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight24.6 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDP14678
NoteGene ID: 6628; UniProt: P14678; Chromosome: 20p13; Predicted MW: 24.6 kDa
FunctionPlays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human SNRPB Polyclonal Antibody
TargetSNRPB

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