Rabbit Anti-ROAA/HNRNPAB Polyclonal Antibody
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产品编号
PAV3433
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别名
heterogeneous nuclear ribonucleoprotein A/B, ABBP1, HNRPAB
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | heterogeneous nuclear ribonucleoprotein A/B, ABBP1, HNRPAB |
| Catalog Number | PAV3433 |
| Product Description | Rabbit polyclonal antibody raised against human HNRNPAB (Heterogeneous nuclear ribonucleoprotein A/B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | HNRNPAB |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human HNRNPAB protein (UniProt: Q99729) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 3182 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈36.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 36.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q99729 |
| Note | Gene ID: 3182; UniProt: Q99729; Chromosome: 5q35.3; Predicted MW: 36.2 kDa |
| Function | Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human HNRNPAB Polyclonal Antibody |
| Target | HNRNPAB |
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