Rabbit Anti-RFOX1/RBFOX1 Polyclonal Antibody
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产品编号
PAV3329
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别名
RNA binding fox-1 homolog 1, 2BP1, A2BP1, FOX-1, FOX1, HRNBP1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RNA binding fox-1 homolog 1, 2BP1, A2BP1, FOX-1, FOX1, HRNBP1 |
| Catalog Number | PAV3329 |
| Product Description | Rabbit polyclonal antibody raised against human RBFOX1 (RNA binding protein fox-1 homolog 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RBFOX1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Immunogen | This antibody was raised against from part region of human RBFOX1 protein (UniProt: Q9NWB1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 54715 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈42.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.8 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9NWB1 |
| Note | Gene ID: 54715; UniProt: Q9NWB1; Chromosome: 16p13.3; Predicted MW: 42.8 kDa |
| Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RBFOX1 Polyclonal Antibody |
| Target | RBFOX1 |
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