Rabbit Anti-PSF1/GINS1 Polyclonal Antibody
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产品编号
PAV3182
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别名
GINS complex subunit 1, IMD55, PSF1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | GINS complex subunit 1, IMD55, PSF1 |
| Catalog Number | PAV3182 |
| Product Description | Rabbit polyclonal antibody raised against human GINS1 (DNA replication complex GINS protein PSF1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | GINS1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008] |
| Immunogen | This antibody was raised against from part region of human GINS1 protein (UniProt: Q14691) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9837 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈23.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 23.0 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q14691 |
| Note | Gene ID: 9837; UniProt: Q14691; Chromosome: 20p11.21; Predicted MW: 23.0 kDa |
| Function | Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human GINS1 Polyclonal Antibody |
| Target | GINS1 |
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