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Rabbit Anti-PAPD1/MTPAP Polyclonal Antibody
Rabbit Anti-PAPD1/MTPAP Polyclonal Antibody

Rabbit Anti-PAPD1/MTPAP Polyclonal Antibody

产品编号

PAV2924

别名

mitochondrial poly(A) polymerase, PAPD1, SPAX4, TENT6

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasmitochondrial poly(A) polymerase, PAPD1, SPAX4, TENT6
Catalog NumberPAV2924
Product DescriptionRabbit polyclonal antibody raised against human MTPAP (Poly RNA polymerase, mitochondrial). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameMTPAP
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录与RNA加工
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
ImmunogenThis antibody was raised against from part region of human MTPAP protein (UniProt: Q9NVV4)
ApplicationWB
Recommended DilutionWB 1:500-2000
Gene ID55149
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈66.2 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight66.2 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ9NVV4
NoteGene ID: 55149; UniProt: Q9NVV4; Chromosome: 10p11.23; Predicted MW: 66.2 kDa
FunctionPolymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human MTPAP Polyclonal Antibody
TargetMTPAP

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