Rabbit Anti-PAIRB/SERBP1 Polyclonal Antibody
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产品编号
PAV2919
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别名
SERPINE1 mRNA binding protein 1, CGI-55, CHD3IP, HABP4L, Hero45, PAI-RBP1, PAIRBP1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SERPINE1 mRNA binding protein 1, CGI-55, CHD3IP, HABP4L, Hero45, PAI-RBP1, PAIRBP1 |
| Catalog Number | PAV2919 |
| Product Description | Rabbit polyclonal antibody raised against human SERBP1 (SERPINE1 mRNA-binding protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SERBP1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables several functions, including SUMO binding activity; mRNA 3'-UTR binding activity; and translation repressor activity. Involved in PML body organization and ribosome hibernation. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human SERBP1 protein (UniProt: Q8NC51) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 26135 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈45.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 45.0 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q8NC51 |
| Note | Gene ID: 26135; UniProt: Q8NC51; Chromosome: 1p31.3; Predicted MW: 45.0 kDa |
| Function | Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation. Acts via its association with EEF2/eEF2 factor, sequestering EEF2/eEF2 at the A-site of the ribosome and promoting ribosome stabilization and storage in an inactive state (By similarity). May also play a role in the regulation of mRNA stability: binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SERBP1 Polyclonal Antibody |
| Target | SERBP1 |
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