Rabbit Anti-MED22 Polyclonal Antibody
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产品编号
PAV2280
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别名
mediator complex subunit 22, MED24, SRB6, SURF5, surf-5
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | mediator complex subunit 22, MED24, SRB6, SURF5, surf-5 |
| Catalog Number | PAV2280 |
| Product Description | Rabbit polyclonal antibody raised against human MED22 (Mediator of RNA polymerase II transcription subunit 22). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MED22 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein component of the mediator complex, which functions in the regulation of transcription by bridging interactions between gene-specific regulatory factors, RNA polymerase II, and general transcription factors. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013] |
| Immunogen | This antibody was raised against from part region of human MED22 protein (UniProt: Q15528) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6837 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈22.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 22.2 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q15528 |
| Note | Gene ID: 6837; UniProt: Q15528; Chromosome: 9q34.2; Predicted MW: 22.2 kDa |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MED22 Polyclonal Antibody |
| Target | MED22 |
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