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Rabbit Anti-MED11 Polyclonal Antibody
Rabbit Anti-MED11 Polyclonal Antibody

Rabbit Anti-MED11 Polyclonal Antibody

产品编号

PAV2277

别名

mediator complex subunit 11, HSPC296, NDDRSB

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasmediator complex subunit 11, HSPC296, NDDRSB
Catalog NumberPAV2277
Product DescriptionRabbit polyclonal antibody raised against human MED11 (Mediator of RNA polymerase II transcription subunit 11). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameMED11
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录与RNA加工
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundMED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
ImmunogenThis antibody was raised against from part region of human MED11 protein (UniProt: Q9P086)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID400569
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈13.1 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight13.1 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ9P086
NoteGene ID: 400569; UniProt: Q9P086; Chromosome: 17p13.2; Predicted MW: 13.1 kDa
FunctionComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human MED11 Polyclonal Antibody
TargetMED11

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