Rabbit Anti-MED11 Polyclonal Antibody
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产品编号
PAV2277
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别名
mediator complex subunit 11, HSPC296, NDDRSB
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目录价格
InquiryRMB
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规格
- 100ul
| Alias | mediator complex subunit 11, HSPC296, NDDRSB |
| Catalog Number | PAV2277 |
| Product Description | Rabbit polyclonal antibody raised against human MED11 (Mediator of RNA polymerase II transcription subunit 11). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MED11 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008] |
| Immunogen | This antibody was raised against from part region of human MED11 protein (UniProt: Q9P086) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 400569 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈13.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 13.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9P086 |
| Note | Gene ID: 400569; UniProt: Q9P086; Chromosome: 17p13.2; Predicted MW: 13.1 kDa |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MED11 Polyclonal Antibody |
| Target | MED11 |
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