Rabbit Anti-SYT12 Polyclonal Antibody

产品编号

PAV3896

别名

synaptotagmin 12, sytXII

目录价格

InquiryRMB

规格

100ul

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产品介绍

Alias	synaptotagmin 12, sytXII
Catalog Number	PAV3896
Product Description	Rabbit polyclonal antibody raised against human SYT12 (Synaptotagmin-12). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	SYT12
Species	Human, Rat, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	突触与髓鞘
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010]
Immunogen	This antibody was raised against from part region of human SYT12 protein (UniProt: Q8IV01)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	91683
Tag	Unconjugated
Cross-reactivity	Human, Rat, Mouse
Predicted Molecular Weight	≈46.5 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	46.5 kDa
Cross-reactivity	Human, Rat, Mouse
Uniprot ID	Q8IV01
Note	Gene ID: 91683; UniProt: Q8IV01; Chromosome: 11q13.2; Predicted MW: 46.5 kDa
Function	Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids (By similarity). Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity).
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SYT12 Polyclonal Antibody
Target	SYT12