Rabbit Anti-STX17 Polyclonal Antibody
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产品编号
PAV3866
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别名
syntaxin 17
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | syntaxin 17 |
| Catalog Number | PAV3866 |
| Product Description | Rabbit polyclonal antibody raised against human STX17 (Syntaxin-17). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | STX17 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 突触与髓鞘 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables SNAP receptor activity; SNARE binding activity; and protein phosphatase binding activity. Involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; endoplasmic reticulum-Golgi intermediate compartment organization; and macroautophagy. Acts upstream of or within protein localization to phagophore assembly site. Located in several cellular components, including endoplasmic reticulum-Golgi intermediate compartment; mitochondria-associated endoplasmic reticulum membrane contact site; and vacuolar membrane. Part of SNARE complex. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human STX17 protein (UniProt: P56962) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 55014 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈33.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 33.4 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P56962 |
| Note | Gene ID: 55014; UniProt: P56962; Chromosome: 9q31.1; Predicted MW: 33.4 kDa |
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human STX17 Polyclonal Antibody |
| Target | STX17 |
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