Rabbit Anti-RTN2 Polyclonal Antibody
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产品编号
PAV3499
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别名
reticulon 2, HMNR11, NSP2, NSPL1, NSPLI, SPG12
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | reticulon 2, HMNR11, NSP2, NSPL1, NSPLI, SPG12 |
| Catalog Number | PAV3499 |
| Product Description | Rabbit polyclonal antibody raised against human RTN2 (Reticulon-2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RTN2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 突触与髓鞘 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Reticulon proteins also play an important role in the replication of positive-strand RNA (ssRNA) viruses. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Aug 2020] |
| Immunogen | This antibody was raised against from part region of human RTN2 protein (UniProt: O75298) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6253 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈59.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 59.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | O75298 |
| Note | Gene ID: 6253; UniProt: O75298; Chromosome: 19q13.32; Predicted MW: 59.3 kDa |
| Function | Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RTN2 Polyclonal Antibody |
| Target | RTN2 |
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