Rabbit Anti-R4RL2/RTN4RL2 Polyclonal Antibody
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产品编号
PAV3231
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别名
reticulon 4 receptor like 2, NGRH1, NgR2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | reticulon 4 receptor like 2, NGRH1, NgR2 |
| Catalog Number | PAV3231 |
| Product Description | Rabbit polyclonal antibody raised against human RTN4RL2 (Reticulon-4 receptor-like 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RTN4RL2 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 突触与髓鞘 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway; negative regulation of neuron projection development; and positive regulation of synapse assembly. Located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human RTN4RL2 protein (UniProt: Q86UN3) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 349667 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈46.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 46.1 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q86UN3 |
| Note | Gene ID: 349667; UniProt: Q86UN3; Chromosome: 11q12.1; Predicted MW: 46.1 kDa |
| Function | Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RTN4RL2 Polyclonal Antibody |
| Target | RTN4RL2 |
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