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Rabbit Anti-P2Y12/P2RY12 Polyclonal Antibody
Rabbit Anti-P2Y12/P2RY12 Polyclonal Antibody

Rabbit Anti-P2Y12/P2RY12 Polyclonal Antibody

产品编号

PAV2897

别名

purinergic receptor P2Y12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc)

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliaspurinergic receptor P2Y12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc)
Catalog NumberPAV2897
Product DescriptionRabbit polyclonal antibody raised against human P2RY12 (P2Y purinoceptor 12))))). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameP2RY12
SpeciesHuman, Rat, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family突触与髓鞘
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
ImmunogenThis antibody was raised against from part region of human P2RY12 protein (UniProt: Q9H244)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID64805
TagUnconjugated
Cross-reactivityHuman, Rat, Mouse
Predicted Molecular Weight≈39.4 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight39.4 kDa
Cross-reactivityHuman, Rat, Mouse
Uniprot IDQ9H244
NoteGene ID: 64805; UniProt: Q9H244; Chromosome: 3q25.1; Predicted MW: 39.4 kDa
FunctionReceptor for ADP and ATP coupled to G proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human P2RY12 Polyclonal Antibody
TargetP2RY12

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