Rabbit Anti-STRAB/STRADB Polyclonal Antibody
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产品编号
PAV3862
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别名
STE20 related adaptor beta, ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038, STLK6
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | STE20 related adaptor beta, ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038, STLK6 |
| Catalog Number | PAV3862 |
| Product Description | Rabbit polyclonal antibody raised against human STRADB (STE20-related kinase adapter protein beta). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | STRADB |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] |
| Immunogen | This antibody was raised against from part region of human STRADB protein (UniProt: Q9C0K7) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 55437 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈47.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 47.0 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9C0K7 |
| Note | Gene ID: 55437; UniProt: Q9C0K7; Chromosome: 2q33.1; Predicted MW: 47.0 kDa |
| Function | Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human STRADB Polyclonal Antibody |
| Target | STRADB |
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