Rabbit Anti-SPRE3/SPRED3 Polyclonal Antibody
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产品编号
PAV3796
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别名
sprouty related EVH1 domain containing 3, Eve-3, spred-3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | sprouty related EVH1 domain containing 3, Eve-3, spred-3 |
| Catalog Number | PAV3796 |
| Product Description | Rabbit polyclonal antibody raised against human SPRED3 (Sprouty-related, EVH1 domain-containing protein 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SPRED3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
| Immunogen | This antibody was raised against from part region of human SPRED3 protein (UniProt: Q2MJR0) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 399473 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈42.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q2MJR0 |
| Note | Gene ID: 399473; UniProt: Q2MJR0; Chromosome: 19q13.2; Predicted MW: 42.7 kDa |
| Function | Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SPRED3 Polyclonal Antibody |
| Target | SPRED3 |
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