Rabbit Anti-SPN90/NCKIPSD Polyclonal Antibody
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产品编号
PAV3792
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别名
NCK interacting protein with SH3 domain, AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NCK interacting protein with SH3 domain, AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH |
| Catalog Number | PAV3792 |
| Product Description | Rabbit polyclonal antibody raised against human NCKIPSD (NCK-interacting protein with SH3 domain). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NCKIPSD |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019] |
| Immunogen | This antibody was raised against from part region of human NCKIPSD protein (UniProt: Q9NZQ3) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 51517 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈79.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 79.0 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9NZQ3 |
| Note | Gene ID: 51517; UniProt: Q9NZQ3; Chromosome: 3p21.31; Predicted MW: 79.0 kDa |
| Function | Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NCKIPSD Polyclonal Antibody |
| Target | NCKIPSD |
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