Rabbit Anti-SOS1 Polyclonal Antibody
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产品编号
PAV3752
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别名
SOS Ras/Rac guanine nucleotide exchange factor 1, GF1, GGF1, GINGF, HGF, NS4, SOS-1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SOS Ras/Rac guanine nucleotide exchange factor 1, GF1, GGF1, GINGF, HGF, NS4, SOS-1 |
| Catalog Number | PAV3752 |
| Product Description | Rabbit polyclonal antibody raised against human SOS1 (Son of sevenless homolog 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SOS1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SOS1 protein (UniProt: Q07889) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6654 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈152.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 152.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q07889 |
| Note | Gene ID: 6654; UniProt: Q07889; Chromosome: 2p22.1; Predicted MW: 152.5 kDa |
| Function | Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3/ERK1 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SOS1 Polyclonal Antibody |
| Target | SOS1 |
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