Rabbit Anti-SNX33 Polyclonal Antibody
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产品编号
PAV3739
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别名
sorting nexin 33, SH3PX3, SH3PXD3C, SNX30
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | sorting nexin 33, SH3PX3, SH3PXD3C, SNX30 |
| Catalog Number | PAV3739 |
| Product Description | Rabbit polyclonal antibody raised against human SNX33 (Sorting nexin-33). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SNX33 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is involved in cytoskeletal reorganization, vesicle trafficking, endocytosis, and mitosis. The encoded protein is essential for the creation of the cleavage furrow during mitosis and for completion of mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| Immunogen | This antibody was raised against from part region of human SNX33 protein (UniProt: Q8WV41) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 257364 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈65.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 65.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8WV41 |
| Note | Gene ID: 257364; UniProt: Q8WV41; Chromosome: 15q24.2; Predicted MW: 65.3 kDa |
| Function | Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SNX33 Polyclonal Antibody |
| Target | SNX33 |
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