Rabbit Anti-SH2B3 Polyclonal Antibody
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产品编号
PAV3656
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别名
SH2B adaptor protein 3, IDDM20, LNK
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SH2B adaptor protein 3, IDDM20, LNK |
| Catalog Number | PAV3656 |
| Product Description | Rabbit polyclonal antibody raised against human SH2B3 (SH2B adapter protein 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SH2B3 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] |
| Immunogen | This antibody was raised against from part region of human SH2B3 protein (UniProt: Q9UQQ2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10019 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈63.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 63.2 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9UQQ2 |
| Note | Gene ID: 10019; UniProt: Q9UQQ2; Chromosome: 12q24.12; Predicted MW: 63.2 kDa |
| Function | Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SH2B3 Polyclonal Antibody |
| Target | SH2B3 |
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