Rabbit Anti-RPGF4/RAPGEF4 Polyclonal Antibody
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产品编号
PAV3459
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别名
Rap guanine nucleotide exchange factor 4, CAMP-GEFII, CGEF2, EPAC, EPAC 2, EPAC2, Nbla00496
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | Rap guanine nucleotide exchange factor 4, CAMP-GEFII, CGEF2, EPAC, EPAC 2, EPAC2, Nbla00496 |
| Catalog Number | PAV3459 |
| Product Description | Rabbit polyclonal antibody raised against human RAPGEF4 (Rap guanine nucleotide exchange factor 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAPGEF4 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in Rap protein signal transduction; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of postsynapse organization. Predicted to act upstream of or within with a positive effect on hormone secretion. Predicted to act upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; regulation of exocytosis; and secretion by cell. Located in cytosol. Implicated in autistic disorder. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human RAPGEF4 protein (UniProt: Q8WZA2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11069 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈115.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 115.5 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q8WZA2 |
| Note | Gene ID: 11069; UniProt: Q8WZA2; Chromosome: 2q31.1; Predicted MW: 115.5 kDa |
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Does not seem to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAPGEF4 Polyclonal Antibody |
| Target | RAPGEF4 |
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