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Rabbit Anti-RHOQ Polyclonal Antibody
Rabbit Anti-RHOQ Polyclonal Antibody

Rabbit Anti-RHOQ Polyclonal Antibody

产品编号

PAV3369

别名

ras homolog family member Q, ARHQ, HEL-S-42, RASL7A, TC10, TC10A

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasras homolog family member Q, ARHQ, HEL-S-42, RASL7A, TC10, TC10A
Catalog NumberPAV3369
Product DescriptionRabbit polyclonal antibody raised against human RHOQ (Rho-related GTP-binding protein RhoQ). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRHOQ
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family小G蛋白与适配蛋白
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]
ImmunogenThis antibody was raised against from part region of human RHOQ protein (UniProt: P17081)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID23433
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈22.7 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight22.7 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDP17081
NoteGene ID: 23433; UniProt: P17081; Chromosome: 2p21; Predicted MW: 22.7 kDa
FunctionPlasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RHOQ Polyclonal Antibody
TargetRHOQ

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