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Rabbit Anti-RB39B/RAB39B Polyclonal Antibody
Rabbit Anti-RB39B/RAB39B Polyclonal Antibody

Rabbit Anti-RB39B/RAB39B Polyclonal Antibody

产品编号

PAV3290

别名

RAB39B, member RAS oncogene family, BGMR, MRX72, WSMN, WSN, XLID72

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
AliasRAB39B, member RAS oncogene family, BGMR, MRX72, WSMN, WSN, XLID72
Catalog NumberPAV3290
Product DescriptionRabbit polyclonal antibody raised against human RAB39B (Ras-related protein Rab-39B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRAB39B
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family小G蛋白与适配蛋白
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked cognitive disability. [provided by RefSeq, Aug 2013]
ImmunogenThis antibody was raised against from part region of human RAB39B protein (UniProt: Q96DA2)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID116442
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈24.6 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight24.6 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ96DA2
NoteGene ID: 116442; UniProt: Q96DA2; Chromosome: Xq28; Predicted MW: 24.6 kDa
FunctionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation. Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission (By similarity). May regulate the homeostasis of SNCA/alpha-synuclein (By similarity).
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RAB39B Polyclonal Antibody
TargetRAB39B

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