Rabbit Anti-RB39B/RAB39B Polyclonal Antibody
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产品编号
PAV3290
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别名
RAB39B, member RAS oncogene family, BGMR, MRX72, WSMN, WSN, XLID72
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目录价格
InquiryRMB
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规格
- 100ul
| Alias | RAB39B, member RAS oncogene family, BGMR, MRX72, WSMN, WSN, XLID72 |
| Catalog Number | PAV3290 |
| Product Description | Rabbit polyclonal antibody raised against human RAB39B (Ras-related protein Rab-39B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAB39B |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked cognitive disability. [provided by RefSeq, Aug 2013] |
| Immunogen | This antibody was raised against from part region of human RAB39B protein (UniProt: Q96DA2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 116442 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈24.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 24.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96DA2 |
| Note | Gene ID: 116442; UniProt: Q96DA2; Chromosome: Xq28; Predicted MW: 24.6 kDa |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation. Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission (By similarity). May regulate the homeostasis of SNCA/alpha-synuclein (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAB39B Polyclonal Antibody |
| Target | RAB39B |
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