Rabbit Anti-RB22A/RAB22A Polyclonal Antibody
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产品编号
PAV3286
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别名
RAB22A, member RAS oncogene family
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RAB22A, member RAS oncogene family |
| Catalog Number | PAV3286 |
| Product Description | Rabbit polyclonal antibody raised against human RAB22A (Ras-related protein Rab-22A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAB22A |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human RAB22A protein (UniProt: Q9UL26) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 57403 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈21.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 21.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9UL26 |
| Note | Gene ID: 57403; UniProt: Q9UL26; Chromosome: 20q13.32; Predicted MW: 21.9 kDa |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB22A plays a role in endocytosis and intracellular protein transport. Mediates trafficking of transferrin/TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Has low GTPase activity. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAB22A Polyclonal Antibody |
| Target | RAB22A |
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