Rabbit Anti-RASL3/RASAL3 Polyclonal Antibody
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产品编号
PAV3283
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别名
RAS protein activator like 3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RAS protein activator like 3 |
| Catalog Number | PAV3283 |
| Product Description | Rabbit polyclonal antibody raised against human RASAL3 (RAS protein activator like-3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RASAL3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene belongs to the Ras GTPase-activating proteins (RasGAP) family and encodes a protein with pleckstrin homology (PH), C2, and Ras GTPase-activation protein (RasGAP) domains. This protein is localized near or at the plasma membrane when expressed exogenously. Reduced expression of this gene in some cell lines resulted in increased levels of the active form of Ras (Ras-GTP), suggesting that this gene may play a role in negatively regulating the Ras signaling pathway. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017] |
| Immunogen | This antibody was raised against from part region of human RASAL3 protein (UniProt: Q86YV0) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 64926 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈111.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 111.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q86YV0 |
| Note | Gene ID: 64926; UniProt: Q86YV0; Chromosome: 19p13.12; Predicted MW: 111.9 kDa |
| Function | Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down-stream ERK signaling pathway. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RASAL3 Polyclonal Antibody |
| Target | RASAL3 |
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