Rabbit Anti-RAP1B Polyclonal Antibody
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产品编号
PAV3271
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别名
RAP1B, member of RAS oncogene family, K-REV, RAL1B, THC11
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RAP1B, member of RAS oncogene family, K-REV, RAL1B, THC11 |
| Catalog Number | PAV3271 |
| Product Description | Rabbit polyclonal antibody raised against human RAP1B (Ras-related protein Rap-1b). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAP1B |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011] |
| Immunogen | This antibody was raised against from part region of human RAP1B protein (UniProt: P61224) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5908 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈20.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 20.8 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P61224 |
| Note | Gene ID: 5908; UniProt: P61224; Chromosome: 12q15; Predicted MW: 20.8 kDa |
| Function | GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAP1B Polyclonal Antibody |
| Target | RAP1B |
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