首页
>>
产品中心
>>
抗体产品
>>
一抗
>>
信号转导
>>
小G蛋白与适配蛋白
>
Rabbit Anti-RAB43 Polyclonal Antibody
Rabbit Anti-RAB43 Polyclonal Antibody

Rabbit Anti-RAB43 Polyclonal Antibody

产品编号

PAV3246

别名

RAB43, member RAS oncogene family, RAB11B, RAB41

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
AliasRAB43, member RAS oncogene family, RAB11B, RAB41
Catalog NumberPAV3246
Product DescriptionRabbit polyclonal antibody raised against human RAB43 (Ras-related protein Rab-43). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRAB43
SpeciesHuman
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family小G蛋白与适配蛋白
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundEnables G protein activity. Involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of Golgi organization; and retrograde transport, plasma membrane to Golgi. Located in Golgi membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; and phagocytic vesicle. Is active in cis-Golgi network membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jun 2026]
ImmunogenThis antibody was raised against from part region of human RAB43 protein (UniProt: Q86YS6)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID339122
TagUnconjugated
Cross-reactivityHuman
Predicted Molecular Weight≈23.3 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight23.3 kDa
Cross-reactivityHuman
Uniprot IDQ86YS6
NoteGene ID: 339122; UniProt: Q86YS6; Chromosome: 3q21.3; Predicted MW: 23.3 kDa
FunctionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Required for the structural integrity of the Golgi complex. Also controls the anterograde ER-to-Golgi transport of nascent G protein-coupled receptors (including ADRA2A, ADRA2B, ADRA2C, ADRA1B, ADRB2 and AGTR1) and regulates the ER sorting of GPCR members by virtue of its ability to interact directly. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RAB43 Polyclonal Antibody
TargetRAB43

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价