Rabbit Anti-RAB43 Polyclonal Antibody
-
产品编号
PAV3246
-
别名
RAB43, member RAS oncogene family, RAB11B, RAB41
-
目录价格
InquiryRMB
-
规格
- 100ul
| Alias | RAB43, member RAS oncogene family, RAB11B, RAB41 |
| Catalog Number | PAV3246 |
| Product Description | Rabbit polyclonal antibody raised against human RAB43 (Ras-related protein Rab-43). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAB43 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables G protein activity. Involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of Golgi organization; and retrograde transport, plasma membrane to Golgi. Located in Golgi membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; and phagocytic vesicle. Is active in cis-Golgi network membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human RAB43 protein (UniProt: Q86YS6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 339122 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈23.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 23.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q86YS6 |
| Note | Gene ID: 339122; UniProt: Q86YS6; Chromosome: 3q21.3; Predicted MW: 23.3 kDa |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Required for the structural integrity of the Golgi complex. Also controls the anterograde ER-to-Golgi transport of nascent G protein-coupled receptors (including ADRA2A, ADRA2B, ADRA2C, ADRA1B, ADRB2 and AGTR1) and regulates the ER sorting of GPCR members by virtue of its ability to interact directly. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAB43 Polyclonal Antibody |
| Target | RAB43 |
0