Rabbit Anti-PROF2/PFN2 Polyclonal Antibody
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产品编号
PAV3158
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别名
profilin 2, D3S1319E, PFL
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | profilin 2, D3S1319E, PFL |
| Catalog Number | PAV3158 |
| Product Description | Rabbit polyclonal antibody raised against human PFN2 (Profilin-2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PFN2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PFN2 protein (UniProt: P35080) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5217 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈15.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 15.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P35080 |
| Note | Gene ID: 5217; UniProt: P35080; Chromosome: 3q25.1; Predicted MW: 15.0 kDa |
| Function | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PFN2 Polyclonal Antibody |
| Target | PFN2 |
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