Rabbit Anti-NOG1/GTPBP4 Polyclonal Antibody
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产品编号
PAV2553
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别名
GTP binding protein 4, CRFG, NGB, NOG1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | GTP binding protein 4, CRFG, NGB, NOG1 |
| Catalog Number | PAV2553 |
| Product Description | Rabbit polyclonal antibody raised against human GTPBP4 (GTP-binding protein 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | GTPBP4 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 小G蛋白与适配蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human GTPBP4 protein (UniProt: Q9BZE4) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 23560 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈74.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 74.0 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q9BZE4 |
| Note | Gene ID: 23560; UniProt: Q9BZE4; Chromosome: 10p15.3; Predicted MW: 74.0 kDa |
| Function | Involved in the biogenesis of the 60S ribosomal subunit. Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human GTPBP4 Polyclonal Antibody |
| Target | GTPBP4 |
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