Rabbit Anti-TRIB2 Polyclonal Antibody
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产品编号
PAV4128
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别名
tribbles pseudokinase 2, C5FW, GS3955, TRB2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | tribbles pseudokinase 2, C5FW, GS3955, TRB2 |
| Catalog Number | PAV4128 |
| Product Description | Rabbit polyclonal antibody raised against human TRIB2 (Tribbles homolog 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TRIB2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | This antibody was raised against from part region of human TRIB2 protein (UniProt: Q92519) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 28951 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈38.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 38.8 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q92519 |
| Note | Gene ID: 28951; UniProt: Q92519; Chromosome: 2p24.3; Predicted MW: 38.8 kDa |
| Function | Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TRIB2 Polyclonal Antibody |
| Target | TRIB2 |
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