Rabbit Anti-TPSN/TAPBP Polyclonal Antibody
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产品编号
PAV4110
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别名
TAP binding protein, MHC1D3, NGS17, TAPA, TPN, TPSN
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TAP binding protein, MHC1D3, NGS17, TAPA, TPN, TPSN |
| Catalog Number | PAV4110 |
| Product Description | Rabbit polyclonal antibody raised against human TAPBP (Tapasin). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TAPBP |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TAPBP protein (UniProt: O15533) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6892 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈47.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 47.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | O15533 |
| Note | Gene ID: 6892; UniProt: O15533; Chromosome: 6p21.32; Predicted MW: 47.6 kDa |
| Function | Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TAPBP Polyclonal Antibody |
| Target | TAPBP |
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