Rabbit Anti-STK38 Polyclonal Antibody
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产品编号
PAV3858
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别名
serine/threonine kinase 38, NDR, NDR1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | serine/threonine kinase 38, NDR, NDR1 |
| Catalog Number | PAV3858 |
| Product Description | Rabbit polyclonal antibody raised against human STK38 (Serine/threonine-protein kinase 38). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | STK38 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
| Immunogen | This antibody was raised against from part region of human STK38 protein (UniProt: Q15208) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11329 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈54.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 54.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q15208 |
| Note | Gene ID: 11329; UniProt: Q15208; Chromosome: 6p21.31; Predicted MW: 54.2 kDa |
| Function | Serine/threonine-protein kinase that acts as a negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. Acts as an ufmylation 'reader' in a kinase-independent manner: specifically recognizes and binds mono-ufmylated histone H4 in response to DNA damage, promoting the recruitment of SUV39H1 to the double-strand breaks, resulting in ATM activation. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human STK38 Polyclonal Antibody |
| Target | STK38 |
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