Rabbit Anti-SKAP1 Polyclonal Antibody
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产品编号
PAV3690
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别名
src kinase associated phosphoprotein 1, HEL-S-81p, SCAP1, SKAP55
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | src kinase associated phosphoprotein 1, HEL-S-81p, SCAP1, SKAP55 |
| Catalog Number | PAV3690 |
| Product Description | Rabbit polyclonal antibody raised against human SKAP1 (Src kinase-associated phosphoprotein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SKAP1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SKAP1 protein (UniProt: Q86WV1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8631 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈41.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 41.4 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q86WV1 |
| Note | Gene ID: 8631; UniProt: Q86WV1; Chromosome: 17q21.32; Predicted MW: 41.4 kDa |
| Function | Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SKAP1 Polyclonal Antibody |
| Target | SKAP1 |
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