Rabbit Anti-SIK2 Polyclonal Antibody
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产品编号
PAV3683
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别名
salt inducible kinase 2, LOH11CR1I, QIK, SIK-2, SNF1LK2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | salt inducible kinase 2, LOH11CR1I, QIK, SIK-2, SNF1LK2 |
| Catalog Number | PAV3683 |
| Product Description | Rabbit polyclonal antibody raised against human SIK2 (Serine/threonine-protein kinase SIK2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SIK2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in intracellular signal transduction; positive regulation of ERAD pathway; and protein autophosphorylation. Is active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human SIK2 protein (UniProt: Q9H0K1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 23235 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈103.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 103.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9H0K1 |
| Note | Gene ID: 23235; UniProt: Q9H0K1; Chromosome: 11q23.1; Predicted MW: 103.9 kDa |
| Function | Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism. Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. Phosphorylates EP300 and thus inhibits its histone acetyltransferase activity. In turn, regulates the DNA-binding ability of several transcription factors such as PPARA or MLXIPL. Also plays a role in thymic T-cell development (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SIK2 Polyclonal Antibody |
| Target | SIK2 |
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