Rabbit Anti-RIOK2 Polyclonal Antibody
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产品编号
PAV3377
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别名
RIO kinase 2, RIO2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RIO kinase 2, RIO2 |
| Catalog Number | PAV3377 |
| Product Description | Rabbit polyclonal antibody raised against human RIOK2 (Serine/threonine-protein kinase RIO2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RIOK2 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable protein kinase activity. Involved in several processes, including positive regulation of rRNA processing; positive regulation of ribosomal small subunit export from nucleus; and regulation of mitotic metaphase/anaphase transition. Located in cytoplasm. Part of preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human RIOK2 protein (UniProt: Q9BVS4) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 55781 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈63.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 63.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9BVS4 |
| Note | Gene ID: 55781; UniProt: Q9BVS4; Chromosome: 5q15; Predicted MW: 63.3 kDa |
| Function | Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RIOK2 Polyclonal Antibody |
| Target | RIOK2 |
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