Rabbit Anti-P4K2A/PI4K2A Polyclonal Antibody
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产品编号
PAV2902
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别名
phosphatidylinositol 4-kinase type 2 alpha, NEDMSB, PI4KII, PIK42A
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphatidylinositol 4-kinase type 2 alpha, NEDMSB, PI4KII, PIK42A |
| Catalog Number | PAV2902 |
| Product Description | Rabbit polyclonal antibody raised against human PI4K2A (Phosphatidylinositol 4-kinase type 2-alpha). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PI4K2A |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM, Mar 2008] |
| Immunogen | This antibody was raised against from part region of human PI4K2A protein (UniProt: Q9BTU6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 55361 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈54.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 54.0 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q9BTU6 |
| Note | Gene ID: 55361; UniProt: Q9BTU6; Chromosome: 10q24.2; Predicted MW: 54.0 kDa |
| Function | Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PI4K2A Polyclonal Antibody |
| Target | PI4K2A |
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