Rabbit Anti-NEK1 Polyclonal Antibody
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产品编号
PAV2497
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别名
NIMA related kinase 1, ALS24, NY-REN-55, OFD2, SRPS2, SRPS2A, SRTD6
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NIMA related kinase 1, ALS24, NY-REN-55, OFD2, SRPS2, SRPS2A, SRTD6 |
| Catalog Number | PAV2497 |
| Product Description | Rabbit polyclonal antibody raised against human NEK1 (Serine/threonine-protein kinase Nek1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NEK1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| Immunogen | This antibody was raised against from part region of human NEK1 protein (UniProt: Q96PY6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 4750 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈142.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 142.8 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96PY6 |
| Note | Gene ID: 4750; UniProt: Q96PY6; Chromosome: 4q33; Predicted MW: 142.8 kDa |
| Function | Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis (By similarity). Involved in cilium assembly. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NEK1 Polyclonal Antibody |
| Target | NEK1 |
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