Rabbit Anti-MYLK2 Polyclonal Antibody
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产品编号
PAV2420
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别名
myosin light chain kinase 2, KMLC, MLCK, MLCK2, skMLCK
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | myosin light chain kinase 2, KMLC, MLCK, MLCK2, skMLCK |
| Catalog Number | PAV2420 |
| Product Description | Rabbit polyclonal antibody raised against human MYLK2 (Myosin light chain kinase 2, skeletal/cardiac muscle). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MYLK2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human MYLK2 protein (UniProt: Q9H1R3) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 85366 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈64.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 64.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9H1R3 |
| Note | Gene ID: 85366; UniProt: Q9H1R3; Chromosome: 20q11.21; Predicted MW: 64.7 kDa |
| Function | Ca(2+)/calmodulin-dependent kinase that phosphorylates the regulatory light chain (RLC) of sarcomeric myosin in skeletal and cardiac muscle. Phosphorylation of RLC promotes displacement of myosin cross-bridges from the thick filament backbone toward actin-containing thin filaments, increasing the probability of cross-bridge entry into force-generating states and thereby potentiating contractile force at submaximal Ca(2+) concentrations. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MYLK2 Polyclonal Antibody |
| Target | MYLK2 |
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