Rabbit Anti-MK04/MAPK4 Polyclonal Antibody
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产品编号
PAV2315
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别名
mitogen-activated protein kinase 4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | mitogen-activated protein kinase 4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK |
| Catalog Number | PAV2315 |
| Product Description | Rabbit polyclonal antibody raised against human MAPK4 (Mitogen-activated protein kinase 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MAPK4 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Immunogen | This antibody was raised against from part region of human MAPK4 protein (UniProt: P31152) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5596 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈65.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 65.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | P31152 |
| Note | Gene ID: 5596; UniProt: P31152; Chromosome: 18q21.1-q21.2; Predicted MW: 65.9 kDa |
| Function | Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MAPK4 Polyclonal Antibody |
| Target | MAPK4 |
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