Rabbit Anti-MAGI3 Polyclonal Antibody
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产品编号
PAV2232
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别名
membrane associated guanylate kinase, WW and PDZ domain containing 3, MAGI-3, dJ730K3.2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | membrane associated guanylate kinase, WW and PDZ domain containing 3, MAGI-3, dJ730K3.2 |
| Catalog Number | PAV2232 |
| Product Description | Rabbit polyclonal antibody raised against human MAGI3 (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MAGI3 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白激酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable GMP kinase activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of JUN kinase activity. Located in cell junction. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human MAGI3 protein (UniProt: Q5TCQ9) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 260425 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈162.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 162.9 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q5TCQ9 |
| Note | Gene ID: 260425; UniProt: Q5TCQ9; Chromosome: 1p13.2; Predicted MW: 162.9 kDa |
| Function | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MAGI3 Polyclonal Antibody |
| Target | MAGI3 |
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