Rabbit Anti-THOP1 Polyclonal Antibody
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产品编号
PAV4020
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别名
thimet oligopeptidase 1, EP24.15, MEPD_HUMAN, MP78, TOP
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | thimet oligopeptidase 1, EP24.15, MEPD_HUMAN, MP78, TOP |
| Catalog Number | PAV4020 |
| Product Description | Rabbit polyclonal antibody raised against human THOP1 (Thimet oligopeptidase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | THOP1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015] |
| Immunogen | This antibody was raised against from part region of human THOP1 protein (UniProt: P52888) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 7064 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈78.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 78.8 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P52888 |
| Note | Gene ID: 7064; UniProt: P52888; Chromosome: 19p13.3; Predicted MW: 78.8 kDa |
| Function | Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human THOP1 Polyclonal Antibody |
| Target | THOP1 |
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