Rabbit Anti-TP4A3/PTP4A3 Polyclonal Antibody
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产品编号
PAV4100
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别名
protein tyrosine phosphatase 4A3, PRL-3, PRL-R, PRL3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protein tyrosine phosphatase 4A3, PRL-3, PRL-R, PRL3 |
| Catalog Number | PAV4100 |
| Product Description | Rabbit polyclonal antibody raised against human PTP4A3 (Protein tyrosine phosphatase type IVA 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PTP4A3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 磷酸酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Immunogen | This antibody was raised against from part region of human PTP4A3 protein (UniProt: O75365) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11156 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈19.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 19.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | O75365 |
| Note | Gene ID: 11156; UniProt: O75365; Chromosome: 8q24.3; Predicted MW: 19.5 kDa |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PTP4A3 Polyclonal Antibody |
| Target | PTP4A3 |
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