Rabbit Anti-PTN21/PTPN21 Polyclonal Antibody
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产品编号
PAV3204
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别名
protein tyrosine phosphatase non-receptor type 21, PTPD1, PTPRL10
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protein tyrosine phosphatase non-receptor type 21, PTPD1, PTPRL10 |
| Catalog Number | PAV3204 |
| Product Description | Rabbit polyclonal antibody raised against human PTPN21 (Tyrosine-protein phosphatase non-receptor type 21). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PTPN21 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 磷酸酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PTPN21 protein (UniProt: Q16825) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11099 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈133.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 133.3 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q16825 |
| Note | Gene ID: 11099; UniProt: Q16825; Chromosome: 14q31.3; Predicted MW: 133.3 kDa |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PTPN21 Polyclonal Antibody |
| Target | PTPN21 |
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