Rabbit Anti-PPM1E Polyclonal Antibody
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产品编号
PAV3129
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别名
protein phosphatase, Mg2+/Mn2+ dependent 1E, CAMKPN, CaMKP-N, POPX1, PP2CH, caMKN
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protein phosphatase, Mg2+/Mn2+ dependent 1E, CAMKPN, CaMKP-N, POPX1, PP2CH, caMKN |
| Catalog Number | PAV3129 |
| Product Description | Rabbit polyclonal antibody raised against human PPM1E (Protein phosphatase 1E/calmodulin-dependent protein kinase phosphatase N)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PPM1E |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 磷酸酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
| Immunogen | This antibody was raised against from part region of human PPM1E protein (UniProt: Q8WY54) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 22843 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈84.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 84.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q8WY54 |
| Note | Gene ID: 22843; UniProt: Q8WY54; Chromosome: 17q22; Predicted MW: 84.0 kDa |
| Function | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PPM1E Polyclonal Antibody |
| Target | PPM1E |
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