Rabbit Anti-PP4R1/PPP4R1 Polyclonal Antibody
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产品编号
PAV3122
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别名
protein phosphatase 4 regulatory subunit 1, MEG1, PP4(Rmeg), PP4R1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protein phosphatase 4 regulatory subunit 1, MEG1, PP4(Rmeg), PP4R1 |
| Catalog Number | PAV3122 |
| Product Description | Rabbit polyclonal antibody raised against human PPP4R1 (Serine/threonine-protein phosphatase 4 regulatory subunit 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PPP4R1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 磷酸酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
| Immunogen | This antibody was raised against from part region of human PPP4R1 protein (UniProt: Q8TF05) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9989 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈107.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 107.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q8TF05 |
| Note | Gene ID: 9989; UniProt: Q8TF05; Chromosome: 18p11.22; Predicted MW: 107.0 kDa |
| Function | Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. Plays a role in the inhibition of TNF-induced NF-kappa-B activation by regulating the dephosphorylation of TRAF2.; FUNCTION: (Microbial infection) Participates in merkel polyomavirus-mediated inhibition of NF-kappa-B by bridging viral small tumor antigen with NEMO. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PPP4R1 Polyclonal Antibody |
| Target | PPP4R1 |
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