Rabbit Anti-MVP Polyclonal Antibody
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产品编号
PAV2397
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别名
major vault protein, LRP, VAULT1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | major vault protein, LRP, VAULT1 |
| Catalog Number | PAV2397 |
| Product Description | Rabbit polyclonal antibody raised against human MVP (Major vault protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MVP |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 磷酸酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
| Immunogen | This antibody was raised against from part region of human MVP protein (UniProt: Q14764) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9961 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈99.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 99.3 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q14764 |
| Note | Gene ID: 9961; UniProt: Q14764; Chromosome: 16p11.2; Predicted MW: 99.3 kDa |
| Function | Structural component of the vault particle, which is a massive ribonucleoprotein complex that may play a role in cargo transport and signal transduction. Oligomerizes to form a cage-like vault complex, which can house several minor vault components including PARP4. Vaults may play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MVP Polyclonal Antibody |
| Target | MVP |
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