Rabbit Anti-SMOX Polyclonal Antibody
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产品编号
PAV3725
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别名
spermine oxidase, C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | spermine oxidase, C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO |
| Catalog Number | PAV3725 |
| Product Description | Rabbit polyclonal antibody raised against human SMOX (Spermine oxidase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SMOX |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 氧化还原酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012] |
| Immunogen | This antibody was raised against from part region of human SMOX protein (UniProt: Q9NWM0) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 54498 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈61.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 61.8 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9NWM0 |
| Note | Gene ID: 54498; UniProt: Q9NWM0; Chromosome: 20p13; Predicted MW: 61.8 kDa |
| Function | Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SMOX Polyclonal Antibody |
| Target | SMOX |
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