Rabbit Anti-NOXO1 Polyclonal Antibody
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产品编号
PAV2564
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别名
NADPH oxidase organizer 1, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NADPH oxidase organizer 1, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28 |
| Catalog Number | PAV2564 |
| Product Description | Rabbit polyclonal antibody raised against human NOXO1 (NADPH oxidase organizer 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NOXO1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 氧化还原酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012] |
| Immunogen | This antibody was raised against from part region of human NOXO1 protein (UniProt: Q8NFA2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 124056 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈41.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 41.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8NFA2 |
| Note | Gene ID: 124056; UniProt: Q8NFA2; Chromosome: 16p13.3; Predicted MW: 41.3 kDa |
| Function | Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NOXO1 Polyclonal Antibody |
| Target | NOXO1 |
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