Rabbit Anti-NB5R4/CYB5R4 Polyclonal Antibody
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产品编号
PAV2459
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别名
cytochrome b5 reductase 4, NCB5OR, cb5/cb5R, dJ676J13.1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | cytochrome b5 reductase 4, NCB5OR, cb5/cb5R, dJ676J13.1 |
| Catalog Number | PAV2459 |
| Product Description | Rabbit polyclonal antibody raised against human CYB5R4 (Cytochrome b5 reductase 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | CYB5R4 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 氧化还原酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010] |
| Immunogen | This antibody was raised against from part region of human CYB5R4 protein (UniProt: Q7L1T6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 51167 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈59.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 59.5 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q7L1T6 |
| Note | Gene ID: 51167; UniProt: Q7L1T6; Chromosome: 6q14.2; Predicted MW: 59.5 kDa |
| Function | NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human CYB5R4 Polyclonal Antibody |
| Target | CYB5R4 |
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