Rabbit Anti-PORIM/TMEM123 Polyclonal Antibody
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产品编号
PAV3114
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别名
transmembrane protein 123, KCT3, PORIMIN, PORMIN
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | transmembrane protein 123, KCT3, PORIMIN, PORMIN |
| Catalog Number | PAV3114 |
| Product Description | Rabbit polyclonal antibody raised against human TMEM123 (Porimin). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TMEM123 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他结构蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TMEM123 protein (UniProt: Q8N131) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 114908 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈21.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 21.5 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q8N131 |
| Note | Gene ID: 114908; UniProt: Q8N131; Chromosome: 11q22.2; Predicted MW: 21.5 kDa |
| Function | Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TMEM123 Polyclonal Antibody |
| Target | TMEM123 |
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