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Rabbit Anti-TNR27/EDA2R Polyclonal Antibody
Rabbit Anti-TNR27/EDA2R Polyclonal Antibody

Rabbit Anti-TNR27/EDA2R Polyclonal Antibody

产品编号

PAV4093

别名

ectodysplasin A2 receptor, EDA-A2R, EDAA2R, TNFRSF27, XEDAR

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasectodysplasin A2 receptor, EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Catalog NumberPAV4093
Product DescriptionRabbit polyclonal antibody raised against human EDA2R (Tumor necrosis factor receptor superfamily member 27). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameEDA2R
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family其他受体
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]
ImmunogenThis antibody was raised against from part region of human EDA2R protein (UniProt: Q9HAV5)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID60401
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈32.8 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight32.8 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ9HAV5
NoteGene ID: 60401; UniProt: Q9HAV5; Chromosome: Xq12; Predicted MW: 32.8 kDa
FunctionReceptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human EDA2R Polyclonal Antibody
TargetEDA2R

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